Maciej Lech Selected Research

Autoimmune Diseases (Autoimmune Disease)

1/2022	GDF15 Suppresses Lymphoproliferation and Humoral Autoimmunity in a Murine Model of Systemic Lupus Erythematosus.
1/2020	c-Rel gain in B cells drives germinal center reactions and autoantibody production.
1/2018	The Involvement of MicroRNAs in Modulation of Innate and Adaptive Immunity in Systemic Lupus Erythematosus and Lupus Nephritis.
3/2010	Inhibition of Toll-like receptors TLR4 and 7 signaling pathways by SIGIRR: a computational approach.

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Maciej Lech Research Topics

Disease

20	Inflammation (Inflammations) 04/2024 - 04/2013
12	Lupus Nephritis 07/2023 - 12/2006
7	Acute Kidney Injury (Acute Renal Failure) 03/2024 - 09/2009
7	Chronic Renal Insufficiency 04/2023 - 04/2011
7	Fibrosis (Cirrhosis) 01/2019 - 04/2011
6	Necrosis 12/2016 - 08/2010
5	Reperfusion Injury 01/2022 - 01/2012
5	Glomerulonephritis 09/2020 - 11/2006
4	Kidney Diseases (Kidney Disease) 11/2023 - 04/2013
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2023 - 12/2006
4	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 03/2010
3	Nephritis 01/2021 - 09/2020
2	COVID-19 12/2023 - 11/2023
2	Renal Insufficiency (Renal Failure) 01/2022 - 09/2009
2	Proteinuria 09/2020 - 12/2006
2	Kidney Calculi (Kidney Stone) 01/2018 - 03/2017
2	Nephrocalcinosis 01/2018 - 03/2017
2	Bacterial Infections (Bacterial Infection) 01/2017 - 01/2016
2	Atrophy 02/2014 - 04/2011
2	Infections 12/2011 - 11/2006
2	Immune Complex Diseases (Immune Complex Disease) 08/2011 - 08/2007
1	Hypercholesterolemia 10/2022
1	Drug-Related Side Effects and Adverse Reactions 01/2022
1	Rheumatoid Arthritis 01/2022
1	Pneumonia (Pneumonitis) 01/2021
1	Cytokine Release Syndrome 01/2021
1	Hyperuricemia 12/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020
1	Body Weight (Weight, Body) 01/2018
1	Pathologic Processes 01/2018
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2018
1	Primary Hyperoxaluria (Oxaluria, Primary) 03/2017
1	Hyperoxaluria (Oxaluria) 03/2017
1	Bone Resorption 01/2017
1	Periodontitis 01/2017

Drug/Important Bio-Agent (IBA)

8	CytokinesIBA 01/2021 - 08/2010
8	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2017 - 11/2006
7	Proteins (Proteins, Gene)FDA Link 01/2023 - 09/2009
7	Messenger RNA (mRNA)IBA 01/2017 - 09/2009
6	Interleukin-6 (Interleukin 6)IBA 01/2017 - 08/2007
5	Antigen-Antibody Complex (Immune Complex)IBA 10/2022 - 11/2006
4	AutoantibodiesIBA 10/2022 - 12/2006
4	Immunoglobulin G (IgG)IBA 01/2021 - 12/2006
3	DNA (Deoxyribonucleic Acid)IBA 10/2022 - 12/2006
3	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022 - 01/2018
2	Growth Differentiation Factor 15IBA 04/2024 - 09/2020
2	AutoantigensIBA 07/2023 - 09/2013
2	Phosphotransferases (Kinase)IBA 01/2023 - 12/2016
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2020
2	Chemotactic FactorsIBA 01/2021 - 01/2016
2	aristolochic acid I (aristolochic acid)IBA 12/2020 - 01/2018
2	Uric Acid (Urate)IBA 12/2020 - 03/2014
2	ChemokinesIBA 01/2018 - 04/2011
2	Calcium OxalateIBA 01/2018 - 03/2017
2	LigandsIBA 12/2017 - 12/2006
2	Type I Tumor Necrosis Factor ReceptorsIBA 03/2017 - 12/2016
2	Lymphotoxin-alpha (Lymphotoxin)IBA 01/2016 - 11/2012
2	Etanercept (Enbrel)FDA Link 02/2014 - 08/2010
2	Pattern Recognition ReceptorsIBA 09/2013 - 08/2013
2	Clodronic Acid (Clodronate)IBA 08/2010 - 09/2009
2	RNA (Ribonucleic Acid)IBA 08/2007 - 12/2006
2	Imiquimod (Aldara)FDA LinkGeneric 08/2007 - 12/2006
1	Puromycin AminonucleosideIBA 04/2024
1	Immunosuppressive Agents (Immunosuppressants)IBA 03/2024
1	Antiviral Agents (Antivirals)IBA 12/2023
1	Amino Acids FDA Link 11/2023
1	Glucose (Dextrose)FDA LinkGeneric 11/2023
1	Retinaldehyde (Retinal)IBA 11/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2023
1	IndicanIBA 04/2023
1	PeriostinIBA 01/2023
1	SirtuinsIBA 01/2023
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2023
1	UromodulinIBA 01/2023
1	ApelinIBA 01/2023
1	AntibodiesIBA 10/2022
1	Apolipoproteins E (ApoE)IBA 10/2022
1	Deoxyribonucleases (DNase)FDA Link 10/2022
1	Immunomodulating AgentsIBA 01/2022
1	Monocyte Chemoattractant ProteinsIBA 01/2022
1	EndonucleasesIBA 01/2021
1	Adenosine (Adenocard)FDA LinkGeneric 12/2020
1	antiglomerular basement membrane antibodyIBA 09/2020
1	Interferon Regulatory FactorsIBA 01/2019
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2018
1	SilverIBA 01/2018
1	Therapeutic UsesIBA 01/2018
1	MicroRNAs (MicroRNA)IBA 01/2018
1	Cisplatin (Platino)FDA LinkGeneric 01/2018
1	Interleukin-22 (IL-22)IBA 12/2017
1	Type II Tumor Necrosis Factor ReceptorsIBA 03/2017
1	OxalatesIBA 03/2017
1	R-7050IBA 03/2017
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 03/2017
1	Annexin A2 (Annexin II)IBA 03/2017
1	Gingipain Cysteine EndopeptidasesIBA 01/2017
1	Inhibitor of Apoptosis ProteinsIBA 12/2016
1	Cyclophilins (Cyclophilin)IBA 12/2016

Therapy/Procedure

4	Therapeutics 11/2023 - 03/2010
1	Critical Care (Surgical Intensive Care) 12/2023